Modulating The Toxicity And Efficacy Of High Dose Chemotherapy For Multiple Myeloma Through An Intervention To Increase Lean Body Mass
This is a prospective, single-institution, pilot study of a 3 month weight lifting program
designed to increase musle hypertrophy prior to starting stem cell collection and receiving
high-dose melphalan, in patients with multiple myeloma. We will use this exercise
intervention while patients are receiving initial induction chemotherapy in the 3-6 month
period before they receiv high-dose melphalan. The primary study endpoint is to determine
the feasibility of recruiting and retaining multiple myeloma patients to an exercise
intervention trial. The secondary study endpoint is to determine whether the weight lifting
program increases lean body mass as intended.
Interventional
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention
Number of Adverse Events
3-6 months
Yes
United States: Institutional Review Board
UPCC 13412
NCT01809717
March 2013
March 2014
Name | Location |
---|---|
Abramson Cancer Center of the Unviersity of Pennsylvania | Philadelphia, Pennsylvania 19104 |