Cryotherapy Versus Laser for the Treatment of Nongenital Cutaneous Warts: A Randomized Controlled Clinical Trial
Cutaneous warts were a common skin diseases caused by human papilloma virus (HPV) infection.
Although warts may spontaneously resolve, many patients seek for treatment for various
reasons. There are many kinds of treatments for cutaneous warts, including salicylic acid,
cryotherapy, laser, etc. A recent high quality RCT confirmed that the cure rate of topical
salicylic acid and frozen has no difference at six months, but the efficacy of laser versus
cryotherapy on the treatment of warts remains unclear. Therefore, we designed a randomized
controlled trial to test the efficacy of laser versus cryotherapy on the treatment of warts.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
Warts was considered cured if they was no longer visible and could not be palpated anymore by hand. Assessment of whether or not cured was performed on site by a senior dermatologist
Cure rate will be calculated at 16 weeks and 6 months from the first treatment
Shichao Lu, MD
Dermatology Deparment of the 306 Hospital of PLA
China: Ethics Committee