Know Cancer

or
forgot password

Multicentric 5-year Follow-up Study to Assess the Efficacy of E-cigarettes as a Tool for Smoking Cessation and to Compare the Risk of Smoking-related Diseases Among Electronic and Traditional Cigarette Smokers, and Smokers of Both.


N/A
30 Years
80 Years
Not Enrolling
Both
Cardiovascular Diseases, Chronic Obstructive Pulmonary Diseases, Cancer of the Lung, Cancer of the Bladder, Cancer of the Stomach

Thank you

Trial Information

Multicentric 5-year Follow-up Study to Assess the Efficacy of E-cigarettes as a Tool for Smoking Cessation and to Compare the Risk of Smoking-related Diseases Among Electronic and Traditional Cigarette Smokers, and Smokers of Both.


Inclusion Criteria:



- resident into the Abruzzo and Lazio Region

- aged between 30 and 75 years;

- smoker of e-cigarettes (inhaling at least 50 puffs per week) containing nicotine
since six or more months (E-cigarettes only Group);

- smoker of at least one traditional cigarette per day since six or more months
(Traditional cigarettes only Group);

- smoker of both electronic and traditional cigarettes (at least one per day) since six
or more months (Mixed Group).

Exclusion Criteria:

- illicit drug use,

- breastfeeding or pregnancy,

- major depression or other psychiatric conditions,

- severe allergies,

- active antihypertensive medication,

- angina pectoris,

- past episodes of major cardiovascular diseases (myocardial infarction, stroke/TIA,
congestive heart failure, COPD, cancer of the lung, esophagus, larynx, oral cavity,
bladder, pancreas, kidney, stomach, cervix, and myeloid leukemia.

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

Traditional smoking cessation rate

Outcome Description:

Percentage of subjects that were current (in TC and Mixed groups) or former (in EC group) smokers reporting sustained smoking abstinence from traditional cigarette smoking at 60 months. Smoking abstinence is defined as complete abstinence from tobacco smoking (not even a puff) for the 30 days period prior to the visit. This outcome will be self-reported and checked using CO analyzer after breath.

Outcome Time Frame:

5 years

Safety Issue:

No

Principal Investigator

Lamberto Manzoli, MD, MPH

Investigator Role:

Principal Investigator

Investigator Affiliation:

Department of Medicine and Aging Sciences, University of Chieti, Italy

Authority:

Italy: Ministry of Health

Study ID:

CHLM001

NCT ID:

NCT01785537

Start Date:

June 2013

Completion Date:

December 2018

Related Keywords:

  • Cardiovascular Diseases
  • Chronic Obstructive Pulmonary Diseases
  • Cancer of the Lung
  • Cancer of the Bladder
  • Cancer of the Stomach
  • e-cigarette smoking
  • cigarette smoking
  • cardiovascular disease
  • hospitalization
  • chronic obstructive pulmonary diseases
  • observational study
  • efficacy
  • safety
  • Urinary Bladder Neoplasms
  • Cardiovascular Diseases
  • Lung Diseases
  • Respiration Disorders
  • Pulmonary Disease, Chronic Obstructive
  • Lung Neoplasms
  • Stomach Neoplasms
  • Lung Diseases, Obstructive

Name

Location