Type of Study:

Observational

Study Design:

Observational Model: Case-Only, Time Perspective: Prospective

Outcome Measure:

To detect early synchronous second primary esophageal carcinoma

Outcome Description:

To evaluate the use of flexible esophagoscopy and chromoendoscopy with Lugol's solution in the detection of early esophageal carcinomas (second primary carcinomas) in patients with squamous cell carcinoma of the head and neck (HNSCC). All patients with newly diagnosed HNSCC underwent office-based Lugol chromoendoscopy. After flexible esophagoscopy with white light, 3.0% Lugol iodine solution was sprayed over the entire esophageal mucosa. Areas with less-intense staining (LVLs) were evaluated and biopsies taken.

Outcome Time Frame:

The primary measure was assessed immediately after the completion of the study by individual patients.

Safety Issue:

No

Principal Investigator

Pavel Kominek, MD, PhD, MSc

Investigator Role:

Principal Investigator

Investigator Affiliation:

University Hospital Ostrava

Authority:

Czech Republic: State Institute for Drug Control

Study ID:

RVO-FNOs/2012

NCT ID:

NCT01783158

Start Date:

January 2004

Completion Date:

December 2012

Related Keywords:

• Squamous Cell Carcinomas of the Head and Neck
• head and neck carcinoma
• chromoendoscopy
• Lugol's solution
• esophageal carcinoma
• synchronous tumors
• deglutition
• deglutition disorders
• Newly diagnosed HNSCC
• Carcinoma
• Carcinoma, Squamous Cell
• Esophageal Diseases
• Esophageal Neoplasms
• Head and Neck Neoplasms