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Barrett's Esophagus Patient Registry


N/A
18 Years
N/A
Open (Enrolling)
Both
Barrett Esophagus, Esophageal Adenocarcinoma, Gastroesophageal Reflux

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Trial Information

Barrett's Esophagus Patient Registry


Inclusion Criteria:



- Barrett's (BE): Patients who have Barrett's esophagus (all stages: Barrett's
metaplasia, low-grade dysplasia, high-grade dysplasia) based upon standard endoscopic
and histologic criteria.

- Adenocarcinoma (EAC): Patients who have esophageal adenocarcinoma.

- The control cohort will include patients ages 18 and older with no prior history of
BE and EAC. These may include patients who are being seen or have been previously
seen at MGH GI Associates for conditions including gastroesophageal reflux disease,
peptic esophagitis, eosinophilic esophagitis, esophageal motility disorders such as
achalasia and nutcracker esophagus.

Exclusion Criteria:

- Inability or unwillingness to provide blood samples.

- History of known bleeding disorders.

- Currently awaiting organ transplantation.

- Having an acute or severe chronic illness such as congestive heart failure or any
other condition that would prohibit performing the endoscopy.

Type of Study:

Observational [Patient Registry]

Study Design:

Observational Model: Case Control, Time Perspective: Prospective

Outcome Measure:

Progression to esophageal adenocarcinoma

Outcome Time Frame:

5 years (on average although follow-up will continue)

Safety Issue:

No

Authority:

United States: Institutional Review Board

Study ID:

2010P002224

NCT ID:

NCT01776346

Start Date:

January 2011

Completion Date:

December 2021

Related Keywords:

  • Barrett Esophagus
  • Esophageal Adenocarcinoma
  • Gastroesophageal Reflux
  • Adenocarcinoma
  • Adenocarcinoma, Mucinous
  • Barrett Esophagus
  • Esophageal Diseases
  • Gastroesophageal Reflux

Name

Location

Massachusetts General HospitalBoston, Massachusetts  02114-2617