Inclusion Criteria:

- Cigarette smokers who call the New York State Smokers' Quitline requesting assistance
with quitting smoking

- State that they are under the care of a primary care physician

- Are eligible for receipt of pharmacotherapy by mail using the standard NRT criteria

- Speak English

- Answer "no" to the following 3 questions:

- "Have you ever been diagnosed with or treated for a mental health problem like
major depression, bipolar disorder, dysthymia, or schizoaffective disorder?"

- "Have you ever had serious thoughts of killing or hurting yourself, ever have
any intention or plan to carry out these thoughts, or actually attempted to kill
yourself?"

- "Is there any reason that you cannot use varenicline/Chantix?"

Exclusion Criteria:

- State that they are not under the care of a primary care physician

- Are not eligible for receipt of pharmacotherapy by mail using the standard NRT
criteria

- Do not speak English

- Answer "yes" to the question, "have you ever been diagnosed with or treated for a
mental health problem like major depression, bipolar disorder, dysthymia, or
schizoaffective disorder?"

- Answer "yes" to the question, "have you ever had serious thoughts of killing or
hurting yourself, ever have any intention or plan to carry out these thoughts, or
actually attempted to kill yourself?"

- Answer "yes" to the question, "is there any reason that you cannot use
varenicline/Chantix?"

- Are women who are currently pregnant

- Report that they are unwilling to receive or take varenicline on screening