A Randomized Controlled Trial of Acute Surgical Trauma and Stress Response of Laparoscopic Versus Open Left Hemihepatectomy for Liver Benign Lesions
N/A
18 Years
70 Years
18 Years
70 Years
Open (Enrolling)
Both
Benign Lesions in Left Liver
Both
Benign Lesions in Left Liver
Trial Information
A Randomized Controlled Trial of Acute Surgical Trauma and Stress Response of Laparoscopic Versus Open Left Hemihepatectomy for Liver Benign Lesions
Inclusion Criteria:
- patient with benign lesions who requires left hemihepatectomy
- Child-Pugh classification of A to B
- American Society Of Anesthesiologists (ASA) grading of I to III
- a body mass index of between 18 and 35
- willingness to participate in the study
- able to understand the nature of the study and what will be required of them
Exclusion Criteria:
- pregnant or lactating women
- unwillingness to participate
- Child-Pugh classification of C
- ASA grading of IV to V
- with condition of acute inflammatory,fever or diabetes mellitus
- with autoimmune disease or immunodeficiency
- taking drugs that affect the immune system
Type of Study:
Interventional
Study Design:
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
Outcome Measure:
Plasma C-reactive protein (CRP) level
Outcome Description:
CRP will be tested before operation, 3,12,24 hours and 3,5,7 days after operation
Outcome Time Frame:
up to 7 days
Safety Issue:
No
Authority:
China: Ministry of Health
Study ID:
SRRSH20121225-1
NCT ID:
NCT01768728
Start Date:
December 2012
Completion Date:
Related Keywords:
- Benign Lesions in Left Liver
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