Comparison of Sequencing and PNA Clamping of EGFR Gene in Patients With Non-Small Cell Type Lung Cancer
Single arm, open label, prospective, observational study of gefitinib treatment for locally
advanced (stage IIIB) or IV (metastatic) or relapsed NSCLC patients.
Using DNA acquired from tumor tissue, sequencing and PNA-clamping for EGFR gene will be
performed. The detection rates of EGFR mutation will be compared using paired samples.
Observational
Observational Model: Cohort, Time Perspective: Prospective
Detection rate of EGFR mutation
To prove higher detection rate of EGFR mutation with PNA clamping compared with sequencing
two weeks
No
Young-Chul Kim, MD, PhD
Principal Investigator
Chonnam National University Hospital
Korea: Institutional Review Board
ISSIRES0066
NCT01767974
January 2013
June 2015
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