Comparison of O-type Hybrid Knife and IT Knife in Endoscopic Submucosal Dissection for Upper Gastrointestinal Neoplasms: a Prospective Randomized Controlled Trial
Endoscopic submucosal dissection (ESD) has been accepted as an minimal invasive alternative
to surgery for localized early upper gastrointestinal neoplasms recently. However, the
procedure remains to be technically challenging and time consuming. Many modified methods or
newly developed devices were developed to simplify the procedure. A new insulated tip
dissecting knife (O-type Hybrid knife) has been recently developed with both injection and
lateral cutting capability. The aim of this study was to investigate whether ESD procedure
could be shortened with this new device.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
Procedure time for ESD
The time to finish the whole ESD procedure.
up to 1 day
Xijing Hospital of Digestive Diseases
China: Ministry of Health