Know Cancer

or
forgot password

Prospective Validation of the Use of the Freund Clock Drawing Test (CDT) to Screen for Cognitive Dysfunction in Cancer Patients Undergoing Comprehensive Geriatric Assessment (CGA)


N/A
70 Years
N/A
Open (Enrolling)
Both
Elderly Cancer Patients, Cognitive Impairment

Thank you

Trial Information

Prospective Validation of the Use of the Freund Clock Drawing Test (CDT) to Screen for Cognitive Dysfunction in Cancer Patients Undergoing Comprehensive Geriatric Assessment (CGA)


Design: A prospective, observational, cohort study. All geriatric patients who are diagnosed
with cancer will be screened by an oncology clinical nurse specialist or study collaborator
with the G8 questionnaire. Patients who screen positive, will be refered to the
multi-disciplinary onco-geriatric program where a member of the geriatric oncology team will
implement a comprehensive geriatric evaluation under supervision of an oncologist and/or
geriatrician, who will then formulate recommendations and might suggest referral to other
health care providers.

Population: All consenting patients, aged ≥ 70, who are referred for anti-cancer treatment
in the General Hospital Groeninge and who are in need of a CGA.


Inclusion Criteria:



- Patients should have reached the age of 70 or more at the moment of enrolment

- Patients should be eligible for standard CGA as per local practice (e.g. on the basis
of positive screening with G8 or referred by a treating physician on the basis of
clinical suspicion of vulnerability or frailty)

- Histologically confirmed diagnosis of cancer. All stages of cancer are eligible.

- Patients should be fluent in Dutch or French

- Patients must receive their primary oncology care (surgery, course of (neo)adjuvant
or palliative chemotherapy, radiotherapy, targeted therapy, palliative care,
experimental treatment as part of a clinical trial,...) planned in the General
Hospital Groeninge

- Patients can be included before or at the start of a line of treatment but not during
a line of treatment

- Patients should have signed informed consent

Exclusion Criteria:

- Patients who do not match the inclusion criteria

- Patients who are visiting the oncology clinic for a second opinion and do not wish to
be treated in the General Hospital Groeninge

- Patients who already started a respective line of treatment

- Patients deemed fit on the basis of negative screening (negative result on G8) unless
the treating physician suspects vulnerability or frailty based on clinical judgement

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

Validation of the Freund Clock Drawing Test, and its predefined cut-off of ≤ 4, as a screening tool to identify elderly cancer patients in need of a more in-depth cognitive evaluation with the Folstein MMSE within comprehensive geriatric assessment

Outcome Description:

Validation of the Freund Clock Drawing Test by use of Receiver Operating Characteristic (ROC) analysis

Outcome Time Frame:

Baseline

Safety Issue:

No

Authority:

Belgium: Ethics Committee

Study ID:

AZGS2012061

NCT ID:

NCT01749995

Start Date:

November 2012

Completion Date:

October 2014

Related Keywords:

  • Elderly Cancer Patients
  • Cognitive Impairment
  • Elderly cancer patients
  • Screening tool
  • Cognitive impairment
  • Freund Clock Drawing Test
  • Cognition Disorders

Name

Location