Randomized Controlled Trial of Endobronchial Ultrasound Guided Fine Needle Aspiration Techniques
Consecutive patients with suspected malignant peribronchial masses or lymph nodes undergoing
endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) will be
enrolled. All participants will have 4 needle aspirations of each targeted peribronchial
lesion. Two needle aspirations will be performed while applying suction and 2 needle
aspirations will be performed without applying suction in random order. The investigators
will compare the diagnostic yield and the quality of the specimens obtained using the two
techniques.
Interventional
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Diagnostic
Sensitivity of each needle aspiration technique for diagnosis of malignancy
A pathologist blinded to the needle aspiration technique will review the specimen obtained from each needle aspiration and will assess for presence of malignant cells. The sensitivity for diagnosing malignancy will be calculated and compared for the two needle aspiration technique.
Diagnosis of malignancy will be ascertained after 6 month clinical follow up
No
Hassan Chami, MD
Principal Investigator
American University of Beirut Medical Center
Lebanon: The American University of Beirut and Ministry of Health
AmericanUBMC
NCT01741571
October 2012
December 2013
Name | Location |
---|