Catheter Resistance Monitoring to Predict Catheter-Associated Adverse Events in Children and Adolescents: A Feasibility Study
Weekly measurement of catheter resistance will be determined using the Alaris® Syringe
Module (Carefusion Inc., San Diego, USA), a commercially available, FDA-approved intravenous
(IV) pump which is able to deliver accurate flow-rates and obtain accurate pressure
measurements. The inline pressure will be measured at multiple flow-rates and resistance
will be estimated from the gradient of the pressure-flow curve.
- To describe the feasibility of weekly CRM in children and adolescents treated at St.
- To describe patient and caregiver adherence with weekly CRM in children and adolescents
treated at St. Jude.
- To explore the correlation between results of CRM and catheter occlusion or
Observational Model: Cohort, Time Perspective: Prospective
Proportion of attended CRM visits which produce usable resistance data for all lumens of the CVAD
To describe the feasibility of CRM in children and adolescents treated at St. Jude, the proportion of attended CRM visits which produce usable resistance data for all lumens of the CVAD will be recorded for each participant, and summary statistics, including median, range and standard deviation will be reported for the study population.
Weekly for 12 weeks from study entry or until discontinuation of CRM, whichever is shorter
Joshua Wolf, MBBS
St. Jude Children's Research Hospital
United States: Institutional Review Board
|St. Jude Children's Research Hospital||Memphis, Tennessee 38105-2794|