A Comparison of Ingenol Mebutate and Cryotherapy for Treatment of Actinic Keratoses.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
Change from baseline in visual assessment scores at 3 months
The visual assessment evaluates seven clinical signs: erythema, edema, wheal vesiculation, ulceration, hemorrhage, purpura, and crusting. Each sign is assigned a score of 0 to 3, where a score of 0 is associated with no expression of the clinical sign and a better outcome, and a score of 3 is associated with severe expression of the clinical sign and a worse outcome.
Baseline and 3 months
Murad Alam, MD
United States: Institutional Review Board
|Northwestern University Feinberg School of Medicine, Department of Dermatology||Chicago, Illinois 60611|