Inclusion Criteria:

1. Female subjects between, and including, 18 and 45 years of age at the first
vaccination;

2. Healthy subjects as established by medical history and history-oriented clinical
examination;

3. Be able to understand and comply with the request of the protocol;

4. Without acute cervicitis;

5. Not pregnant;

6. Have intact cervix.

Exclusion Criteria:

1. Use of any investigational or non-registered product (drug or vaccine)within 30 days
preceding the first vaccination, or plan to use during the study period;

2. Are using immunosuppressants;

3. Administration of immunoglobulin and/or any blood products within the three months
preceding the first vaccination or planned administration during the study period;

4. Vaccinated of inactivated vaccine 14 days or attenuated vaccine 21 days before the
enrollment;

5. Fever;

6. Concurrently participating another clinical trial;

7. Has received vaccines against HPV 16/18 ;

8. Immunodeficient;

9. History of allergic disease;

10. Serious medical disorders;

11. Blood coagulation disorders;

12. Epilepsy;

13. Unable to comply with protocol due to the mental illness;

14. Visible Condyloma;

15. Pregnant or breast-feeding women;

16. vergins;

17. Have more than 4 sexual partners.