Inclusion Criteria:

- Perimenopausal women between the ages of 45-55; perimenopause is defined as absence
of a menstrual period for 6-18 months.

- Willing to be randomized and compliant to the 3 study groups (whole cruciferous
vegetable intake, cruciferous supplement or placebo tablets)

- Able to give informed consent.

Exclusion Criteria:

- Urinary 2:16 > or = 2.

- Current kidney or liver disease, adrenalectomy, or oophorectomy.

- Use of tobacco products within the preceding three months, illegal use of medications
or use of illegal drugs or substances.

- Current use of antibiotics, cimetidine or black cohosh.

- Systemic administration of estrogen, or use of non-prescription hormones, tamoxifen,
or diabetes medication within the last three months.

- Women under a physician-directed diet or those with a strong dislike of Brassica
vegetables.

- Presence of cancer in the last 5 years, with the exception of fully resected basal or
squamous cell tumors.

- Participation in an investigational drug study in the last 30 days.