Know Cancer

or
forgot password

Vasopressin Versus Norepinephrine for the Management of Septic Shock in Cancer Patients


Phase 3
18 Years
N/A
Open (Enrolling)
Both
Septic Shock

Thank you

Trial Information

Vasopressin Versus Norepinephrine for the Management of Septic Shock in Cancer Patients


Inclusion Criteria:



- Solid neoplasm needing ICU

- Septic Shock according standard criteria

Exclusion Criteria:

- Younger than 18 years;

- Pregnancy;

- Raynaud's phenomenon, systemic sclerosis or vasospastic diathesis;

- Severe hyponatremia (Na<130mEq/L);

- Acute mesenteric ischemia;

- Acute myocardial infarction;

- Cardiogenic shock;

- Current use of vasopressor before randomization

- Expected ICU stay less than 24 hours

- Enrolled in another study;

- Refusal to consent.

Type of Study:

Interventional

Study Design:

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Outcome Measure:

28-day mortality

Outcome Description:

Mortality from all causes in 28-day follow-up

Outcome Time Frame:

28-day from randomization

Safety Issue:

Yes

Principal Investigator

Cristiane M Zambolim, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Department of Anesthesia and Critical Care, Intensive Care Unit - ICESP

Authority:

Brazil: National Committee of Ethics in Research

Study ID:

91762

NCT ID:

NCT01718613

Start Date:

November 2012

Completion Date:

December 2013

Related Keywords:

  • Septic Shock
  • Shock
  • Shock, Septic

Name

Location