Use of 18F-FLT Positron Emission Tomography to Evaluate the Suspicious Findings on Mammography and Breast Ultrasound: A Pilot Study
1. To investigate the diagnostic accuracy of 18F-FLT PET for the suspicious lesions on
mammograms and ultrasound, using the pathologic result of biopsy as gold standard, and
to determine whether 18F-FLT PET can increase the specificity in breast lesion
diagnosis and thus reduce the unnecessary biopsy.
2. To evaluate whether 18F-FLT PET is a cost-effective imaging modality for breast cancer
Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Diagnostic
To investigate the diagnostic accuracy of 18F-FLT PET for the suspicious lesions on mammograms and ultrasound, using the pathologic result of biopsy as gold standard.
The biopsy procedures will be scheduled as soon as possible and should be finished within 2 months after 18F-FLT PET.
Jane Wang, PhD
National Taiwan University Hospital
United States: Food and Drug Administration