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The Effect of Resistance Exercise Frequency in Breast and Gynecologic Cancer Survivors

18 Years
Open (Enrolling)
Breast Cancer, Gynecologic Cancer, Ovarian Cancer, Uterine Cancer, Cervical Cancer

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Trial Information

The Effect of Resistance Exercise Frequency in Breast and Gynecologic Cancer Survivors

As a result of cancer and its treatment, survivors of breast and gynecologic cancer are
reported to have deficits in both physical and psycho-social health. In cancer survivors
exercise has been shown to improve fitness, increase bone density and lean body mass,
enhance self-esteem, and reduce fatigue. These changes have a positive effect on the
survivor's physical functioning and quality of life. However, there are few studies which
have examined the effects of strength training or studies aimed at determining optimal
exercise prescription in this population. Therefore, the purpose of this study is to compare
two strength training prescriptions (once-a-week vs. twice-a-week strength training) to
determine which prescription (if any) results in greater benefit for survivors. It is hoped
that the results of this study will lead to a better understanding of how strength training
improves the health of survivors and will help inform future exercise guidelines for this

Inclusion Criteria:

- Female Survivor of Breast or Gynecologic Cancer

- Completed Primary Treatment (hormone treatments are ok)

- 18 years of age or older

- Physician's Permission to Participate

Exclusion Criteria:

- High Risk Individuals (determined by questionnaire)

- Secondary Health Problems that could increase the risk of participating (Includes but
not limited to: Uncontrolled angina/hypertension, heart failure, osteoporosis, brain
metastases, history of seizures).

- Report participating in a strength training program in the past six (6) months

- Have had a change in medication in the past 30 days

Type of Study:


Study Design:

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Screening

Outcome Measure:

Changes in Muscular Strength

Outcome Description:

Muscular Strength will be assessed using the predicted one-repetition maximum method (Brzycki method)using the bench press and leg press to measure upper and lower body strength.

Outcome Time Frame:

Baseline (end of week 1); Midpoint (end of week 7); Final (end of week 13)

Safety Issue:


Principal Investigator

Scott Grandy, Ph D

Investigator Role:

Principal Investigator

Investigator Affiliation:



Canada: Health Canada

Study ID:




Start Date:

November 2012

Completion Date:

May 2013

Related Keywords:

  • Breast Cancer
  • Gynecologic Cancer
  • Ovarian Cancer
  • Uterine Cancer
  • Cervical Cancer
  • Cancer
  • Breast Cancer
  • Gynecologic Cancer
  • Strength Training
  • Exercise
  • Physical Activity
  • Fatigue
  • Quality of Life
  • Strength
  • Fitness
  • Cancer Survivor
  • Survivor
  • Breast Neoplasms
  • Uterine Cervical Neoplasms
  • Ovarian Neoplasms
  • Uterine Neoplasms