Trial Information
The Effects of Intermittent Epidural Bolus Versus Continuous Epidural Infusion on Fever for Labor Analgesia in Primiparous Women
Inclusion Criteria:
- Nulliparous women
- Required labor analgesia
- Chinese
- Spontaneous labor
Exclusion Criteria:
- Contraindications for epidural analgesia
- Allergic to opioids and/or local anesthetics
- Failed to performing epidural catheterization
- Organic dysfunction
- Those who were not willing to or could not finish the whole study at any time
- Using or used in the past 14 days of the monoamine oxidase inhibitors
- Alcohol addictive or narcotic dependent patients
- Subjects with a nonvertex presentation or scheduled induction of labor
- Twin gestation and breech presentation
Type of Study:
Interventional
Study Design:
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment
Outcome Measure:
Maternal oral temperature
Outcome Time Frame:
At time of initiation of analgesia and hourly thereafter until 4 hours postpartum (approximately 12 hours)
Safety Issue:
Yes
Principal Investigator
Shanwu Feng, M.D.
Investigator Role:
Study Director
Investigator Affiliation:
Nanjing Medical University
Authority:
China: Ethics Committee
Study ID:
NJMCHH-2012-A010
NCT ID:
NCT01708668
Start Date:
October 2012
Completion Date:
August 2013
Related Keywords:
- Labor Pain
- Pain
- Neurologic Manifestations
- Signs and Symptoms
- Pathological Conditions, Signs and Symptoms
- Fever
- Patient controlled epidural analgesia
- Labor analgesia
- Epidural analgesia
- Combined spinal-epidural analgesia
- Neurologic Manifestations
- Signs and Symptoms
- Labor Pain