Inclusion Criteria:

- Phenotypic and genotypic treatment-related symptom associations will be evaluated in
children and adolescents 3-18 years of age with a diagnosis of leukemia.

Exclusion Criteria:

- Children without a definite diagnosis of leukemia will be excluded.

- Children must be able to understand and answer the questions on the questionnaires.

- Children with have a cognitive impairment (e.g. Down syndrome) will not be able to
complete the questionnaires and will not be eligible for the study.