Inclusion Criteria:

- Consecutive patients over a 1-year period referred for EUS examination due to
suspected pancreatic lesions will be enrolled.

- Age 21 years and above.

- Ability to provide informed consent

Exclusion Criteria:

Patients with clinical conditions that preclude the use of DEFINITY™ will be excluded.
These conditions are:

- Right-to-left, bi-directional, or transient right-to-left cardiac shunts;

- Worsening or clinically unstable congestive heart failure;

- Acute myocardial infarction or acute coronary syndromes;

- Serious ventricular arrhythmias or high risk for arrhythmias due to prolongation of
the QT interval;

- Respiratory failure;

- Severe emphysema, pulmonary emboli or other conditions that cause pulmonary
hypertension due to compromised pulmonary arterial vasculature;

- Hypersensitivity to DEFINITY™ or its components.