Prospective Controlled Study of Transbronchial Cryoprobe Versus Forceps Biopsy for Acute Rejection in Lung Transplantation
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
Differences in size of biopsy specimen and architectural preservation of the airways/alveoli (ie degree of crush artifact)
Direct measurements of pathologic specimens from the forceps and cryoprobe will be compared. In addition, amount of crush artifact will alse be directly measured and compared utilizing pathology software which measures area of viable tissue.
From date of study enrollment until the patient is 2 years post lung transplant
Johns Hopkins University
United States: Institutional Review Board
|Johns Hopkins Hospital||Baltimore, Maryland 21287|