Molecularly Imprinted Polymer Sensors of Modified Nucleosides for Non-invasive Monitoring of Cancer Therapy : Effect of Chemotherapy on Cancerous Proliferation Based on the Dynamic Excretion of Urinary Nucleosides.
Observational
Observational Model: Case-Only, Time Perspective: Prospective
Effect of chemotherapy on urinary excretion of modified nucleosides
1 urine sample per day 3 days before and 14 days after beginning of chemotherapy Measurement of modified nucleosides, cortisol and 6-sulfatoxymelatonin concentration 1 saliva sample : Measurement of Clock genes polymorphisms expression
17 days
No
Francis Lévi, MD PhD
Principal Investigator
INSERM CNRS AP-HP Université Paris Sud
France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)
C11-59
NCT01693861
September 2012
August 2013
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