A Multi-centre, Randomised, Investigator-blinded Study Comparing the Polyp Detection Rate of Two Different Types of Bowel Preparation: a 2-litre Solution (MOVIPREP®) Versus a Hyperosmotic and Stimulant Combined Low Volume Bowel Preparation (Sodium Picosulfate and Magnesium Citrate)
- Patient's written informed consent must be obtained prior to inclusion.
- Male or female outpatients or inpatients aged 40 to 80 years with an indication for
- Willing to undergo a colonoscopy for diagnostic or surveillance purposes
- Patients with a known personal of familial risk of colon neoplasia, willing to
undergo a screening colonoscopy
- Willing, able and competent to complete the entire procedure and to comply with study
- Females of childbearing potential must employ an adequate method of contraception.
- History of gastric emptying disorders.
- History of ileus, toxic megacolon, gastrointestinal obstruction and colonic
- History of phenylketonuria.
- Known glucose-6-phosphate dehydrogenase deficiency.
- Known hypersensitivity to macrogol 3350, sodium sulphate or ascorbic acid/sodium
- History of colonic resection.
- Requirement for permanent medication and associated stable serum concentrations (e.g.
- Presence of congestive heart failure (NYHA III + IV).
- Acute life-threatening cardiovascular disease.
- Documented history of severe renal insufficiency (creatinine clearance <30 ml/min).
- Other contraindication described in the summary of product characteristics (SmPC) of
- Patient has a condition, clinically significant laboratory results, or is in a
situation which, in the investigator's opinion, may put the patient at significant
risk, may confound the study results, or may interfere significantly.
- Application of any unlicensed medication within the previous 3 months or
participation in any other research study in the last 3 months.
- Females who are pregnant, nursing or planning a pregnancy.
- Patients who, in the opinion of the investigator, may not be compliant with the study
- Previous participation in this clinical study.