Inclusion Criteria:

- Patient who is less than 2 years

- Patient who has been diagnosed with superficial infantile hemangioma

- The tumor which has been in proliferative or plateau phase

- There is no indication for systemic treatment

- Informed consent is obtained from the parent of the patient

Exclusion Criteria:

- Patient who has the indication for systemic therapy

- Patient who is treated by the other modality such as laser treatment

- Patient who has underlying disease treated by beta blocker, corticosteroids,
interferon, cyclophosphamide or vincristine

- Patient who has history of hypersensitivity reaction to beta blocker, asthma, cardiac
condition prove to heart block