Optical Tomographic Imaging of Infantile Hemangiomas
Infantile hemangiomas (IH) are common vascular growths that frequently arise in infants. The
clinical presentation is variable, and some hemangiomas have the potential to cause
disfiguring and even lifethreatening complications. While there is no FDA approved treatment
for IH, certain medications have been shown to be effective in shrinking the growths.
Unfortunately, there is no objective tool to monitor IH or to guide treatment. Such a tool
would improve the management of these patients. A new handheld wireless device uses diffuse
optical imaging (DOI) technology to measure blood flow characteristics.
The device has been used in studies to assess patients with breast cancer. Optical
tomography has also been increasingly used to assess neurological function and pathology in
The goal of the investigators' study is to assess the utility of DOI for characterizing and
monitoring IH. Fifteen IH will be assessed at three points in time as part of this study,
comprising two groups: 'Natural History' and 'Treatment'. DOI measurements will be
correlated with clinical findings and existing ultrasound measurements of the IH.
Observational Model: Cohort
United States: Food and Drug Administration
|Columbia University Medical Center / Department of Dermatology||New York, New York 10032|