Inclusion Criteria

CHILD INCLUSION CRITERIA:

- St. Jude Children's Research Hospital (SJCRH) patient with a diagnosis of cancer or
sickle cell disease (to include genotypes HbSS, HbSC, HbSβ°thal, HbSβ+thal, HbSD,
HbSO, Hb S/HPFH, HbSE).

- <18 years of age at time of enrollment.

- For patients with cancer, those who are at least one month from diagnosis (to include
patients in active treatment section, as well as, survivors in After Completion of
Therapy clinic).

CHILD EXCLUSION CRITERIA:

- For patients with cancer, those who have relapsed or had disease recurrence within
the past month.

- For patients with cancer, those who have progressive disease.

- In medical crisis, as determined by consultation with the patient's primary care
physician.

- On transplant service.

- On inpatient service or expected/scheduled inpatient admission (e.g. hospitalized).

- Experiencing current acute complications of sickle cell disease requiring
hospitalization or an acute care visit (e.g., pain crises, acute chest syndrome,
acute cerebrovascular events/stroke or active infection/fever, etc.).

PARENT INCLUSION CRITERIA:

- One parent, who is 18 years of age or older, per family of a SJCRH patient who meets
criteria.

- Current smoker (defined as having smoked cigarettes in the past 30 days, as based on
self-report.)

- Reads and speaks English.

- Has the cognitive capacity to complete study questionnaires.

- Willing and able to provide informed consent according to institutional guidelines.

PARENT EXCLUSION CRITERIA:

- In crisis or distress or have another disabling condition that would preclude
participation as determined by consultation with patient's primary care physician
and/or social worker prior to study enrollment.