Cohort Study of Patients With IgG4-Related Disease
Immunoglobulin G4-related disease (IgG4-RD) is a recently defined emerging clinical entity
characterized by tissue infiltration by IgG4-positive plasma cells, tissue fibrosclerosis
and elevated serum IgG4 concentration.
In this study, patients with IgG4-RD will be investigated, including clinical presentation,
laboratory findings and imaging study. All patients will be treated by standard care and
follow-uped for at least 6 months.
Observational Model: Cohort, Time Perspective: Prospective
Clinical Response is measured by IgG4-RD Responder Index, including organ/site score and serum IgG4 level.
Wen Zhang, MD
Deptment of Rheumatology, Peking Union Medical College Hospital
China: National Natural Science Foundation