Comparison the Hemodynamics Effects Between Dexmedetomidine and Propofol in Major Abdominal Surgical Patients
18 Years
N/A
Both
Abdominal Tumor, Intestinal Obstruction, Cirrhosis, Intestinal Fistula, Aneurism
Trial Information
Comparison the Hemodynamics Effects Between Dexmedetomidine and Propofol in Major Abdominal Surgical Patients
When the patients can be roused, they will first receive analgesia with bolus of fentanyl
0.03mg, followed by a continuous infusion at a fixed dose of 0.3μg/kg/h during study period.
Then patients will be randomly divided into two groups (Dexmedetomidine and Propofol). All
of them will receive hemodynamic monitoring through "Vigileo"(Edwards Lifesciences) and
cardiogram monitor. The study will continue for 6-24 hours.
Inclusion Criteria:
1. Postoperative patients of major abdominal surgery
2. Age ≧ 18
Exclusion Criteria:
1. heart rate ≤ 50 bpm
2. allergy with dexmedetomidine or propofol
3. pregnancy
Type of Study:
Observational
Study Design:
Observational Model: Case Control, Time Perspective: Prospective
Outcome Measure:
Cardiac output
Outcome Time Frame:
the study will start when the patient can be roused after major abdominal surgery and will continue for 6 to 24hours
Safety Issue:
Yes
Principal Investigator
minying chen, MD
Investigator Role:
Principal Investigator
Investigator Affiliation:
study principal investigator
Authority:
China: Ethics Committee
Study ID:
IRB[2012]260
NCT ID:
NCT01669044
Start Date:
May 2012
Completion Date:
December 2012
Related Keywords:
- Abdominal Tumor
- Intestinal Obstruction
- Cirrhosis
- Intestinal Fistula
- Aneurism
- Abdominal Neoplasms
- Aneurysm
- Fistula
- Intestinal Fistula
- Intestinal Obstruction
- Liver Cirrhosis
- Fibrosis
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