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Investigating Serotonin Signalling in IBD Patients


N/A
19 Years
85 Years
Open (Enrolling)
Both
Inflammatory Bowel Disease

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Trial Information

Investigating Serotonin Signalling in IBD Patients


Inclusion Criteria:



- Patient groups: Disease diagnosis (CD or UC),duration of disease, previous/type of
treatments, duration of treatment and disease prognosis.

- Healthy controls: No diagnosis of CD or UC and no diagnosis of IBS.

Exclusion Criteria:

- Patient groups: Drugs that directly affect components of 5-HT signaling, any other
disease or condition that may interfere with study assessments as judged by the
investigator.

- Healthy controls:Chronic use of any anti-inflammatory drugs, drugs that directly
affect components of 5-HT signalling and any other disease or condition that may
interfere with study assessments as judged by the investigator.

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

Colonic 5-HT levels

Outcome Time Frame:

At the time of tissue collection

Safety Issue:

No

Principal Investigator

Waliul I Khan, MBBS, PhD.

Investigator Role:

Principal Investigator

Investigator Affiliation:

Dept. of Pathology & Molecular Medicine, McMaster University, Hamilton, Canada.

Authority:

Canada: Ethics Review Committee

Study ID:

12-239

NCT ID:

NCT01650311

Start Date:

July 2012

Completion Date:

May 2013

Related Keywords:

  • Inflammatory Bowel Disease
  • IBD, CD, UC, Serotonin, 5-HT
  • Inflammatory Bowel Diseases
  • Intestinal Diseases

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