Identification of Differentially Expressed Proteins in Parathyroid Tumors and Their Clinical Correlation With the Disease
15 Years
65 Years
Both
Primary Hyperparathyroidism, Hypercalcemia
Trial Information
Identification of Differentially Expressed Proteins in Parathyroid Tumors and Their Clinical Correlation With the Disease
Subjects:
All the PHPT patients attending outdoor patient clinic of Endocrinology and General Surgery
department of Nehru Hospital, PGIMER, Chandigarh will be enrolled in this study.
Sample collection:
A parathyroid tissue sample will be taken from the patients undergoing for
parathyroidectomy. Samples will be collected immediately after surgery, snap frozen and
stored at -80oC until use. In addition 10 ml of blood will also be taken from these patients
for estimating biochemical parameters.
Controls:
Normal parathyroid gland will be used as control and it will be obtained from patient
undergoing thyroidectomy for multinodular goiter as an elective procedure at the institute.
Inclusion Criteria:
- PHPT patients with parathyroid adenoma, hyperplasia and carcinoma
Exclusion Criteria:
- Patients with family history, HPT-JT syndrome and familial isolated
hyperparathyroidism
Type of Study:
Observational
Study Design:
Observational Model: Case Control, Time Perspective: Cross-Sectional
Principal Investigator
Sanjay Kr Bhadada, DM
Investigator Role:
Principal Investigator
Investigator Affiliation:
Associate Professor, Department of Endocrinology, PGIMER Chandigarh India
Authority:
India: Indian Council of Medical Research
Study ID:
parathyroid tumorigenesis
NCT ID:
NCT01647503
Start Date:
July 2012
Completion Date:
Related Keywords:
- Primary Hyperparathyroidism
- Hypercalcemia
- parathyroid gland
- primary hyperparathyroidism
- proteins
- Hypercalcemia
- Hyperparathyroidism
- Parathyroid Neoplasms
- Hyperparathyroidism, Primary
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