Pilot Functional Imaging Study to Evaluate Mechanisms Underlying Chronic Pain in Breast Cancer Patients
Women with breast cancer who either have chronic pain or who do not have chronic pain will
be asked to enroll. Those who participate will have pictures taken of their brain using MRI
when they are lying still and also when pressure is being applied to their thumbnails. These
pictures will be compared to patients without breast cancer who do not have pain and to
those who have other types of pain, such as fibromyalgia. By taking and analyzing these
pictures the investigators hope to understand more about why breast cancer survivors develop
pain after their diagnosis and treatment. In the future the investigators hope to better
treat the pain or possibly even prevent the pain from occurring in the first place.
Observational Model: Cohort, Time Perspective: Cross-Sectional
Determination of differences in pain sensitivity and fMRI in different groups of patients.
The primary objective of this pilot trial is to determine if there may be differences in mechanical pain sensitivity and fMRI brain activation patterns in breast cancer survivors with chronic pain as compared to breast cancer patients without chronic pain, to patients with fibromyalgia, or to healthy controls.
Lynn Henry, MD
University of Michigan Cancer Center
United States: Institutional Review Board
|University of Michigan Comprehensive Cancer Center||Ann Arbor, Michigan 48109-0752|