N/A
20 Years
80 Years
20 Years
80 Years
Not Enrolling
Both
Colorectal Cancer
Both
Colorectal Cancer
Trial Information
Inclusion Criteria:
- 1. Histologically confirmed colorectal cancer 2. Non-metastatic cancer (cTNM I, II,
or III) 3. Over 20 years of age 4. Curative resection (R0)
Exclusion Criteria:
- 1. Patient with distant metastasis 2. History of chemotherapy or radiation therapy
for malignancy 3. Patient receiving immunosuppressive or anti-inflammatory treatment
4. Hereditory colorectal cancer 5. Preoperative chemoradiation therapy for colorectal
cancer 6. Pregnancy 7. Emergency
Type of Study:
Observational
Study Design:
Observational Model: Cohort, Time Perspective: Cross-Sectional
Outcome Measure:
Association between immune related cytokine and number of lymph nodes retrieved.
Outcome Description:
Immunity related cytokine - IL-12, IFN-r, GM-CSF, IL-4, TNF-a, IL-6, IL-8, IL-10, TGF-b1, CXCR4, SDF1, HGF, VEGF - expression is assessed using Bioplex assay. Patient serum is taken one day before surgery. Primary tumor and colonic mucosal tissue are taken just after surgery. Bioplex assay is performed after patients' enrollment
Outcome Time Frame:
2 months after surgery
Safety Issue:
No
Authority:
South Korea: Institutional Review Board
Study ID:
2012-08
NCT ID:
NCT01629524
Start Date:
June 2012
Completion Date:
December 2012
Related Keywords:
- Colorectal Cancer
- Colorectal Neoplasms
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