Molecular Taxonomy in Pediatric Cancer- IncRNA Expression in Primary T-ALL
N/A
N/A
Both
Leukemia
Trial Information
Molecular Taxonomy in Pediatric Cancer- IncRNA Expression in Primary T-ALL
OBJECTIVES:
- Characterization of the transcriptomic landscape in diagnosis and relapse of T-cell
acute lymphoblastic leukemia (ALL) and the direct comparison with corresponding
physiological samples (human thymus).
- Perform high-throughput transcriptome ribonucleic acid (RNA) sequencing using matched
diagnostic T-precursor pediatric ALL samples (peripheral blood or bone marrow).
OUTLINE: Archived peripheral blood and bone marrow samples are analyzed for long non-coding
RNA (IncRNA) expression and sequencing.
Inclusion Criteria
DISEASE CHARACTERISTICS:
- Peripheral blood and bone marrow samples from pediatric patients with diagnosed and
relapsed T-ALL
PATIENT CHARACTERISTICS:
- Not specified
PRIOR CONCURRENT THERAPY:
- Not specified
Type of Study:
Observational
Study Design:
N/A
Outcome Measure:
Identification and characterization of IncRNA of pediatric T-cell acute lymphoblastic leukemia
Safety Issue:
No
Principal Investigator
Iannis Aifantis, PhD
Investigator Role:
Principal Investigator
Investigator Affiliation:
New York University School of Medicine
Authority:
United States: Federal Government
Study ID:
CDR0000735509
NCT ID:
NCT01626183
Start Date:
June 2012
Completion Date:
Related Keywords:
- Leukemia
- T-cell childhood acute lymphoblastic leukemia
- recurrent childhood acute lymphoblastic leukemia
- Leukemia
- Leukemia, Lymphoid
- Precursor Cell Lymphoblastic Leukemia-Lymphoma
- Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
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