Molecular Taxonomy in Pediatric Cancer- IncRNA Expression in Primary T-ALL
- Characterization of the transcriptomic landscape in diagnosis and relapse of T-cell
acute lymphoblastic leukemia (ALL) and the direct comparison with corresponding
physiological samples (human thymus).
- Perform high-throughput transcriptome ribonucleic acid (RNA) sequencing using matched
diagnostic T-precursor pediatric ALL samples (peripheral blood or bone marrow).
OUTLINE: Archived peripheral blood and bone marrow samples are analyzed for long non-coding
RNA (IncRNA) expression and sequencing.
Identification and characterization of IncRNA of pediatric T-cell acute lymphoblastic leukemia
Iannis Aifantis, PhD
New York University School of Medicine
United States: Federal Government