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Multidisciplinary Team IntervenTion in CArdio-ONcology


Phase 2
18 Years
N/A
Not Enrolling
Both
Breast Cancer, Lymphoma

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Trial Information

Multidisciplinary Team IntervenTion in CArdio-ONcology


Inclusion Criteria:



- histologically confirmed malignancy (breast or lymphoma);

- scheduled to receive anthracycline and/or trastuzumab-based chemotherapy;

- age ≥ 18 years;

- willing to attend follow-up visits.

Exclusion Criteria:

- physical disability preventing exercise testing or DEXA scan;

- psychiatric disease or disorder precluding informed consent;

- participation in other cardiotoxicity or exercise intervention study;

- contraindication to anti-cancer therapy, including known heart failure,
cardiomyopathy, or baseline LVEF < 50%;

- previous anthracycline or trastuzumab-based therapy;

- previous radiotherapy to thorax.

Type of Study:

Interventional

Study Design:

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care

Outcome Measure:

echocardiography

Outcome Description:

percentage of longitudinal strain from baseline

Outcome Time Frame:

change from baseline to 12 months

Safety Issue:

No

Authority:

Canada: Health Canada

Study ID:

TITAN 102

NCT ID:

NCT01621659

Start Date:

September 2012

Completion Date:

September 2017

Related Keywords:

  • Breast Cancer
  • Lymphoma
  • multidisciplinary team
  • exercise
  • nutrition
  • cardiology
  • physiotherapy
  • imaging
  • Breast Neoplasms
  • Lymphoma

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