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N/A
N/A
N/A
Open (Enrolling)
Female
Breast Cancer

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Trial Information


Inclusion Criteria:



- Patients with breast cancer

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Retrospective

Outcome Measure:

Evaluate the use of advanced quantitative mass spectometry (Super SILAC) as a discovery platform to uncover novel protein biomarkers in tumor

Outcome Description:

SILAC is a method of advanced quantitative mass spectometry that allows whole proteome analysis as comprehensively as transcriptome analysis. It allows quantification of whole-proteome, measure post-translational modifications and map complete interactome of a protein. Super-SILAC, an improvement of the SILAC method, enables the comparison of the amounts of hundreds or thousands of proteins from a particular tissue between different patients. This technology may enable the discovery of novel tumor protein markers that may be important in tumor progression and treatment response.

Authority:

Singapore: Domain Specific Review Boards

Study ID:

2012/00106

NCT ID:

NCT01619514

Start Date:

March 2012

Completion Date:

Related Keywords:

  • Breast Cancer
  • Breast Neoplasms

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