Comparison Between Mediterranean Diet and High Protein Diet in Women With Pcos: Randomized Controlled Trial
Polycystic ovary syndrome (PCOS) is a heterogeneous syndrome affecting 5-10% of women of
reproductive age. It is characterized by elevated circulating insulin, reduced insulin
sensitivity, infertility, hyperandrogenism, and a multitude of symptoms that result in a
decreased quality of life. The elevated insulin characteristic of PCOS is likely to play a
major role in its pathogenesis by reducing insulin sensitivity and stimulating excess
androgen production hence causing an hormonal imbalance.
Low calories diets have shown to improve pcos symptoms but the optimal diet for all pcos
women is still unknown.
In this study, our purpose is to compare two lowering insulin restricted calories diets in
order to find the optimal diet for improving metabolic and endocrin outcomes in pcos women
we will also investigate which diet has the best long lasting compliance.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
improvement in metabolic outcomes of women with pcos
Adam Geva, MD
Clalit Health Services
Israel: Clalit Health Services