Trial Information
Irradiation Modulates the Pharmacokinetics of Anticancer Drugs for Head and Neck Cancer
Inclusion Criteria:
- locally advanced head and neck, nasopharyngeal cancers, who prepares for concurrent
chemoradiation therapy as definitive or adjuvant setting
Exclusion Criteria:
- previous cancer history;abnormal function of liver and kidney, immunol disease or
hematologic disease
Type of Study:
Observational
Study Design:
Observational Model: Case Control, Time Perspective: Prospective
Outcome Measure:
Area under the plasma concentration versus time curve (AUC) of'chemo-drugs"
Outcome Time Frame:
"15, 30, 45, 60, 90, 120 min post‐dose"
Safety Issue:
No
Authority:
Taiwan: Institutional Review Board
Study ID:
FEMH No.:100163-F
NCT ID:
NCT01609114
Start Date:
April 2012
Completion Date:
Related Keywords:
- Head and Neck Cancer
- phenomena and mechanism of RT-PK
- fact for different anticancer drugs
- different part in human
- Head and Neck Neoplasms