Irradiation Modulates the Pharmacokinetics of Anticancer Drugs for Head and Neck Cancer
- locally advanced head and neck, nasopharyngeal cancers, who prepares for concurrent
chemoradiation therapy as definitive or adjuvant setting
- previous cancer history；abnormal function of liver and kidney, immunol disease or
Type of Study:
Observational Model: Case Control, Time Perspective: Prospective
Area under the plasma concentration versus time curve (AUC) of'chemo-drugs"
Outcome Time Frame:
"15, 30, 45, 60, 90, 120 min post‐dose"
Taiwan: Institutional Review Board
- Head and Neck Cancer
- phenomena and mechanism of RT-PK
- fact for different anticancer drugs
- different part in human
- Head and Neck Neoplasms