Risk Stratification-directed Low-dose Glucocorticoid Prophylaxis for Acute GVHD After Unmanipulated Haploidentical Blood and Marrow Transplantation——a Randomized, Controlled, Clinical Trial
N/A
60 Years
Both
Leukemia
Trial Information
Risk Stratification-directed Low-dose Glucocorticoid Prophylaxis for Acute GVHD After Unmanipulated Haploidentical Blood and Marrow Transplantation——a Randomized, Controlled, Clinical Trial
patients undergone haploidentical HSCT following day 5 post transplant were randomized to
treated group(low-dose glucocorticoid) and controlled group(no intervention).
Inclusion Criteria:
- no severe diarrhea no serious infection
Exclusion Criteria:
- serious diarrhea active,uncontrolled infection
Type of Study:
Interventional
Study Design:
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
Outcome Measure:
incidence of acute graft-versus-host disease
Outcome Description:
number of participants with acute graft-versus-host disease at 100 days
Outcome Time Frame:
paticipants will be followed for the duration of hospital stay,an expected average of 100 days
Safety Issue:
No
Authority:
China: Ministry of Health
Study ID:
PUPH IRB [2012] (26)
NCT ID:
NCT01607580
Start Date:
June 2012
Completion Date:
September 2013
Related Keywords:
- Leukemia
- Graft vs Host Disease
- Leukemia
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