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Role of Activin A (ActA) in the Human Cancer Cachexia


N/A
18 Years
N/A
Open (Enrolling)
Both
Colorectal Cancer, Lung Cancer

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Trial Information

Role of Activin A (ActA) in the Human Cancer Cachexia


Inclusion Criteria:



- 18-year-old or older

- Colorectal or lung cancer demonstrated by histology or cytology

- New diagnosis or new recurrence

- Expected survival more than 3 months

- No previous history of other cancer in the last 5 years

- No pregnancy or lactation

- Signed informed consent

Exclusion Criteria:

- Non-caucasian

- Major digestive malabsorption

- Major depression

- Artificial nutrition

- Height doses of steroids (>1 mg/kg hydrocortisone equivalent)

- Hyperthyroidism

- Other causes of malnutrition

- Expected survival less than 3 months

- Severely impaired walking

- Anticoagulants or antiplatelet therapy

- Disability or medical condition which might prevent the compliance to the protocol

- Any conditions which may prevent the compliance to the protocol

- Performance status ECOG > ou = 4

- Participation to other clinical studies

Type of Study:

Interventional

Study Design:

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science

Outcome Measure:

Circulating Activin A level

Outcome Time Frame:

2 years

Safety Issue:

No

Authority:

Belgium: The Federal Public Service (FPS) Health, Food Chain Safety and Environment

Study ID:

ACTICA

NCT ID:

NCT01604642

Start Date:

May 2012

Completion Date:

Related Keywords:

  • Colorectal Cancer
  • Lung Cancer
  • Cachexia
  • Colorectal Neoplasms
  • Lung Neoplasms

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