Trial Information

Imaging Biomarkers of Tissue Microstructure and Vasculature as Predictors of Glioblastoma Multiforme Response to Treatment With Bevacizumab for Progressive Disease

This study is for subjects with a diagnosis of a brain tumor called glioblastoma that is
being treated with bevacizumab. Bevacizumab is a drug that your doctor believes is the best
treatment option available to subjects at this time for this type of tumor. Bevacizumab
affects the growth of blood vessels by tumors such as glioblastoma, thus effectively
starving the tumor of oxygen and food.

Magnetic Resonance Imaging (MRI) is a test done by a machine in the radiology department
that takes pictures of your body using special magnets, rather than X-rays. With a new MRI
scan technique the investigators can take very, very detailed images of the vessel and tumor
structure. This project will allow us to compare the images of vessel and tumor structure to
the effectiveness of Bevacizumab as a treatment option. With this project the investigators
will hopefully develop an accurate way to predict whether or not Bevacizumab will be an
effective treatment option for patients.