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Expression and Subcellular Localization of NEIL3 in Tumors


N/A
N/A
N/A
Open (Enrolling)
Both
Brain and Central Nervous System Tumors

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Trial Information

Expression and Subcellular Localization of NEIL3 in Tumors


OBJECTIVES:

- To determine the expression and subcellular localization of nei endonuclease VIII-like
3 (NEIL3) in brain tumors.

OUTLINE: Tissue microarray samples are analyzed for NEIL3 expression and subcellular
localization by immunohistochemical methods.

Inclusion Criteria


DISEASE CHARACTERISTICS:

- Tissue microarrays (TMA) samples from the Biopathology Core

- Samples from patients diagnosed with brain tumors

- Progenitor, or blast, cell origin

PATIENT CHARACTERISTICS:

- Not specified

PRIOR CONCURRENT THERAPY:

- Not specified

Type of Study:

Observational

Study Design:

N/A

Outcome Measure:

Correlation of NEIL3 expression and/or nuclear localization with tumor type or grade with respect to degree of differentiation

Safety Issue:

No

Principal Investigator

Heithem M. El-Hodiri, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Nationwide Children's Hospital

Authority:

United States: Federal Government

Study ID:

CDR0000732178

NCT ID:

NCT01585389

Start Date:

April 2012

Completion Date:

Related Keywords:

  • Brain and Central Nervous System Tumors
  • adult brain tumor
  • childhood brain tumor
  • Brain Neoplasms
  • Nervous System Neoplasms
  • Central Nervous System Neoplasms

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