Inclusion Criteria:

- Thyroid carcinoma

- Previous thyroidectomy

Exclusion Criteria:

- Potential causes of dry eye (autoimmune diseases, contact lens wearers or drugs that
alter tear production, such as antihistamines and psychotropic)

- Use of other anti-neoplastic, such as 5-fluorouracil and docetaxel, which can cause
epiphora and OVL

- Lacrimal gland / ocular trauma

- Radiation therapy for other diseases or radiotherapy of head and neck

- Patients with diseases that alter the neural control of tear secretion, hormone
therapies, pterygium, Graves' disease with or without ophthalmopathy, blepharitis and
other conditions that may reduce tear production or result in rapid evaporation.