Know Cancer

or
forgot password

Assessment of Cardiac Autonomic Function in Adulthood After Chemotherapy or Radiotherapy in Childhood. Ancillary Study of the "Long-term Follow-up of Childhood Cancer Survivors in the Rhône-Alpes and Auvergne Regions of France" Study


N/A
18 Years
N/A
Open (Enrolling by invite only)
Both
Cancer, Sequels, Complications, Autonomic Nervous System

Thank you

Trial Information

Assessment of Cardiac Autonomic Function in Adulthood After Chemotherapy or Radiotherapy in Childhood. Ancillary Study of the "Long-term Follow-up of Childhood Cancer Survivors in the Rhône-Alpes and Auvergne Regions of France" Study


For this purpose, analysis of the cardiac RR variability is a reliable, non-invasive and
reproducible system that could be used in this population as a tool for early detection of
cardiovascular dysfunction.


Inclusion Criteria:



- Included in the SALTO study

- Having signed the informed consent form

Exclusion Criteria:

- General anesthesia in the two weeks prior to recording

- Known allergy to electrodes

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

Autonomic nervous system activity

Outcome Description:

The autonomic status will be classified in sympatho-vagal equilibrium as "normal", "altered" or "severely abnormal" according to the values obtained for some temporal indices (SDNN, SDaNN, RMSSD etc. ..) and frequencies (Ptot, HF, LF , VLF, ratio LF / HF) compared to validated standards for the age (mean +/- standard deviation).

Outcome Time Frame:

15 years after the end of the cancer treatment

Safety Issue:

No

Principal Investigator

Claire BERGER, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

CHU de Saint-Etienne

Authority:

France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)

Study ID:

1108162

NCT ID:

NCT01574196

Start Date:

September 2012

Completion Date:

March 2014

Related Keywords:

  • Cancer
  • Sequels
  • Complications
  • Autonomic Nervous System
  • Childhood cancer
  • Cancer
  • Sequels
  • Complications
  • Chemotherapy
  • Radiotherapy
  • Surgery
  • Autonomic nervous system
  • Parasympathetic Nervous System
  • Sympathetic Nervous System

Name

Location