Palatability of Experimental Cigarettes
Phase 3: This descriptive study will use a between subjects, double blind design. This study
will test 3 nicotine levels of nicotine, tar and ventilation. Subjects and research
assistants will be blind to the cigarette type.
Allocation: Randomized, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention
Comparison of Urine Cotinine Levels and Total Nicotine Equivalent (TNE)
Two urine cotinine levels are taken, one at baseline and one at week 1, to assess cotinine levels for nicotine exposure. TNE is the sum of nicotine, cotinine, trans 3'-hydroxycotinine and their respective glucouronide conjugates.
Baseline (Day 1) Compared to Week 1
Dorothy Hatsukami, Ph.D.
Tobacco Use Research Program, University of Minnesota
United States: Institutional Review Board
|University of Minnesota||Minneapolis, Minnesota 55455|