Trial Information

Bile and Bile Duct/Pancreatic Duct Brushings Database for Patients With Pancreato-biliary Stricture

Recently, a lot of research has been done to test for certain markers like fluorescence in
situ hybridization (FISH), digital image analysis (DIA), and quantifiable morphometric
results in biliary stricture brushings. Recently, polysomy FISH has been studied as a
promising marker in predicting cancer in a pancreato-biliary stricture. Many genetic,
epigenetic, and protein alterations arise during pancreaticobiliary tumor process. The types
of markers that have been commonly evaluated as diagnostic assays are mutations, chromosomal
gains and losses, and DNA methylation alterations. However there are only a few studies in
this area. Testing for these markers can help determine whether the narrowing or stricture
in your bile duct is cancer or not.