Effectiveness of Colon Capsule Endoscopy as Colorectal Cancer Method of Screening in The Familiar-Risk Population
40 Years
65 Years
Both
Colorectal Cancer, Genetics of
Trial Information
Effectiveness of Colon Capsule Endoscopy as Colorectal Cancer Method of Screening in The Familiar-Risk Population
The purpose of this study is to compare the adherence and effectiveness of colon capsule
endoscopy (CCE-2) versus conventional colonoscopy to screen first-degree relatives of
patients with colorectal cancer.
Inclusion Criteria:
- Asymptomatic first-degree relatives (parents, siblings or children) of CRC patients
aged less than 60 years or with two or more first-degree relatives of any age.
- Signing of informed consent.
Exclusion Criteria:
- Personal history of adenoma or CRC.
- History of hereditary CRC.
- Chronic inflammatory disease.
- Presence of digestive symptoms.
- Patients with swallowing problems (dysphagia).
- Personal history of gastrointestinal surgery.
- Enteritis radioactive.
- Renal failure.
- Congestive heart failure
- Allergy or other contraindication to Bysacodyl to PEG or phosphates.
- Pregnancy.
- Suspected bowel obstruction or intestinal strictures or fistulas known.
- Colectomy.
- Paralysis with impaired intestinal motility.
- Any other process that the investigator's discretion to make inadequate
participation.
Type of Study:
Interventional
Study Design:
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
Outcome Measure:
Participation to colorectal cancer screening in first-degree relatives of patients with colorectal cancer
Outcome Description:
Assess whether colon capsule endoscopy increases participation to colorectal cancer screening in first-degree relatives of patients with colorectal cancer
Outcome Time Frame:
6 month follow up
Safety Issue:
Yes
Principal Investigator
Enrique Quintero, MD. PhD.
Investigator Role:
Principal Investigator
Investigator Affiliation:
Hospital Universitario de Canarias
Authority:
Spain: Ethics Committee
Study ID:
CEC_cribado_CCR
NCT ID:
NCT01557101
Start Date:
April 2012
Completion Date:
June 2013
Related Keywords:
- Colorectal Cancer, Genetics of
- Colorectal Neoplasms
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