Endogenous DNA Transposition in Rhabdoid Tumors
- To investigate the expression and function of PGBD5 in 50 primary rhabdoid tumors.
OUTLINE: Freshly frozen rhabdoid tumors will be studied using fluorescence in situ
hybridization (FISH) and polymerase chain reaction (PCR) to establish the genomic location
of PGBD5. Protein expression in rhabdoid tumor tissue microarrays is also analyzed.
Expression and function of PGBD5 in rhabdoid tumors
Elizabeth A. Mullen, MD
Dana-Farber Cancer Institute
United States: Federal Government