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A Feasibility Study of Circulating microRNAs as Disease Markers in Pediatric Cancers


N/A
3 Years
21 Years
Open (Enrolling)
Both
Leukemia, Lymphoma, Central Nervous System

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Trial Information

A Feasibility Study of Circulating microRNAs as Disease Markers in Pediatric Cancers


Inclusion Criteria:



- All children who are in treatment for leukemia, lymphoblastic lymphoma and central
nervous system tumors

- age: greater than 3 years and less than or equal to 21 years of age

- Patients must be in a phase of their treatment during which routine blood draws,
lumbar punctures or CSF sampling from Ommaya reservoirs are required for treatment of
their cancers.

Exclusion Criteria:

- Patients who have completed treatment and do not require routine blood draws and/or
lumbar punctures

- Patients who are considered too ill to participate as determined by their treating
physician

- Patients with a known genetic condition that predisposed them to the development of
cancer.

Type of Study:

Observational

Study Design:

Observational Model: Case-Only, Time Perspective: Prospective

Outcome Measure:

Determine if miRNAs are present in the blood of patients with pediatric cancers

Outcome Time Frame:

1 year

Safety Issue:

No

Principal Investigator

Rishi Lulla, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Ann & Robert H Lurie Children's Hospital of Chicago

Authority:

United States: Institutional Review Board

Study ID:

2010-14205

NCT ID:

NCT01541800

Start Date:

March 2010

Completion Date:

Related Keywords:

  • Leukemia
  • Lymphoma
  • Central Nervous System
  • Leukemia
  • Lymphoma

Name

Location

Children's Memorial HospitalChicago, Illinois  60614