Cognitive Rehabilitation Group Intervention for Breast Cancer Survivors
Previous pilot work (non-randomized, pre-post design) has shown that this intervention was
effective in improving post-intervention cognitive complaints and neuropsychological (NP)
test performance. Because practice effects may influence NP performance, it is important to
compare the intervention participants to women who are not exposed to the intervention.
Thus, this randomized controlled trial will compare the active intervention to a control
group of patients who will receive the intervention at a delayed time point. The primary
outcomes are improvements in cognitive complaints and NP test performance 2 months after
completion of the intervention program. Quantitative EEG (QEEG) measurements will be used
as a secondary exploratory endpoint to see if this may be an effective biomarker of
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care
Cognitive function measured by neuropsychological assessment 2 months after group intervention
Patricia Ganz, M.D.
Jonsson Comprehensive Cancer Center
United States: Institutional Review Board
|UCLA||Los Angeles, California 90095|